{"signature": "0xbaa8e0ca7cd44cdc37d5b66d39937fd9f3dbce8291ec84b54c833ef22dd3bbbf55d52052b90f3d365ff20bb0ff50785822f866913e9da8476ca71d1133c5e85a1b", "application": {"round": "0xd875fa07bedce182377ee54488f08f017cb163d4", "answers": [{"type": "email", "hidden": true, "question": "Email Address", "questionId": 0, "encryptedAnswer": {"ciphertext": "Op1lTlZ+V2Lm+UVPnfMHITqZvF7oqZNzgqRCc5C7ZnZcz8NbFzXah5qO6S0tPEE9", "encryptedSymmetricKey": "17fed229456a997357b4035a6e18782befaf37d6538099dcbb451acc95f9de2ffb29bcd39af49beff9f3a670300af00388149fc9409b68529bd98a8ff827de3bcbb79df907fe77418152048b73d273c646dddc64a5e2b8ef9d0316e9618ddc861550651f8e42d474498916f4315e8c25b5dd380958a9f76182c7c1a45d74ae02000000000000002046cc7d065f2233f2e2fd77491d1b3ccdda88a9b317702d1ec342603af089b515e6c8538e99ed12da9640e3bc5d61deb8"}}, {"type": "number", "answer": "3", "hidden": false, "question": "Team Size", "questionId": 1}, {"type": "short-answer", "hidden": true, "question": "Your Telegram Handle", "questionId": 2, "encryptedAnswer": {"ciphertext": "VqcA18FJ3DSazHXJ+znubXr2h/pSj0t7AHUCAoGTECo=", "encryptedSymmetricKey": "f0e46f699d77fa79dd803f8e3f24ffc3d4672a684b95c31bc13698095f1a05fd650c57b55f72f1d9f0687c1348ab8e1630e1831a9bdf0e026dad979515a8f13f2d8819c8d0cd9b1d318d9283fcf2cf7fde64523461f29059ca8f7f726e23f6886783ad344230d890f5137e51ffb47ac464fd169c8bdaae49c7b1431cbe8cfe14000000000000002087d47e45585cf086b8f89e24d3f552a74c77d6e2d96f66027bb318cfe7aec5c052c2701562f0d913d88feaf3d1a64fa9"}}, {"type": "link", "answer": "https://t.me/DeSci6551", "hidden": false, "question": "Link to your Public Group Chat (Discord or Telegram )", "questionId": 3}, {"type": "paragraph", "answer": "The project\u2019s idea was piloted during ZuConnect, involving three attendees and integrating ZuPass to create a \"proof of participation\" in the pilot dTrial without revealing their personal information or identity. The code created for this was initially open-sourced here: https://github.com/seeincodes/zuhack-istanbul", "hidden": false, "question": "Please explain how your project meets the round-specific eligibility criteria. ", "questionId": 4}, {"type": "paragraph", "answer": "Our primary focus will be on expanding our 'Total Active Users/Communities,' which encompasses both individual participants and communities engaged as data providers and data analysts. This metric is crucial as it directly reflects the engagement and adoption of our platform, indicating the effectiveness of our technology in meeting the needs of users in the healthcare and research sectors.\n\nWhy These Metric Matter:\n\n- User Engagement: A growing number of active users signifies a strong interest and reliance on our platform, validating the effectiveness and usability of our technology.\n- Data Richness: More active users contribute to a richer data pool, enhancing the accuracy and depth of algorithms and overall data analysis capabilities.\n- Community-Driven Research: An increase in active communities aligns with our goal of democratizing research through our DAO structure, fostering collaborative and transparent scientific discovery.\n\nCurrently, we are in the preliminary phase of our project, focusing on building and refining our infrastructure. We have not yet onboarded active users or communities. Our primary goal is to establish this foundational platform and begin user acquisition. We aim to attract a diverse range of users, from individual users and communities to healthcare professionals and research analysts, showcasing our platform's versatility. Our strategies will include targeted outreach, forming community partnerships, and enhancing the platform to ensure it delivers maximum value and a superior user experience.", "hidden": false, "question": "How do you measure the impact of your project? Please provide examples and/or standard metrics. ", "questionId": 5}, {"type": "short-answer", "answer": "HackZuzalu\u2019s prize money TBD.", "hidden": false, "question": "Total Prior Funding for the project in USD", "questionId": 6}, {"type": "multiple-choice", "answer": "None of the above", "hidden": false, "question": "Which of the following funding sources do you have? Check all that apply", "questionId": 7}, {"type": "short-answer", "answer": "Almost three months.", "hidden": false, "question": "How old (in Months) is the project? (New projects welcome!)", "questionId": 8}, {"type": "short-answer", "answer": "https://github.com/seeincodes https://www.linkedin.com/in/celin-mousa-309b98137/ https://www.linkedin.com/in/knobelsdorf/", "hidden": true, "question": "Profiles or socials of other main team members publicly associated with the project (N/A for solo founders): ", "questionId": 9}, {"type": "link", "hidden": false, "question": "If you have any inchain attestations/impact certificates, please share them share(drop the link)", "questionId": 10}, {"type": "paragraph", "answer": "", "hidden": false, "question": "Anything else you'd like to share about your project, previous work, or other project affiliations?", "questionId": 11}, {"type": "paragraph", "answer": "Our platform offers significant value to the Zuzalu community, especially given their interest in longevity and health optimization. By providing a state-of-the-art, privacy-preserving framework for decentralized clinical trials, Zuzalu, and similar network state initiatives can advance in providing advanced health services. This platform, enhanced by blockchain-ready devices from MCS and the underlying protocol from Transience, offers an ideal environment for conducting research and trials focused on health optimization and longevity, all while maintaining stringent privacy standards. Our ongoing pilots are crucial for refining this process, ensuring that the community has the perfect platform for their specific research needs in a completely confidential manner.", "hidden": false, "question": "How is this valuable to the Zuzalu community?", "questionId": 12}, {"type": "multiple-choice", "answer": "ZuConnect Istanbul", "hidden": false, "question": "Which Zuzalu events have you attended for at least a week? )", "questionId": 13}, {"type": "paragraph", "answer": "Both organizations involved in dTrials have continued to work on parts of the stack that will be necessary for the full product to be readily available to anyone that may want to implement a distributed or fully decentralized trial. MCS continues to focus on making its proprietary hardware the best of its kind and Transience is focusing on the underlying protocol layer to enable a seamless process from data capture and processing to specific tokenomics. Both organizations have a compromise, made public in this application, to make dTrials a long-term decentralized and autonomous project.", "hidden": false, "question": "Please describe the progress of your project? (note: new projects are also welcome)", "questionId": 14}], "project": {"id": "10:0x8e1bD5Da87C14dd8e08F7ecc2aBf9D1d558ea174:1787", "title": "dTrials", "logoImg": "bafkreif5o2shvt2mld7zkkvgjp2kslmhivtbkqr2pfm4b2n3wv7umfmx4q", "metaPtr": {"pointer": "bafkreigjdb5xf4ptfduun6b2uivfyakgimoovdnqitahhmdipff6rvzkqq", "protocol": "1"}, "website": "https://dtrials.gitbook.io/dtrials/", "bannerImg": "bafkreiaisoseebo2ggot2iy6uogw6tphwwaeumkpfnezdz2ulsb7s2xlku", "createdAt": 1706496566889, "userGithub": "kosmostasis", "credentials": {}, "description": "**TL;DR:** dTrials is a hardware and software stack for distributed to fully decentralized clinical trials by MCS Data Labs and Transience.\n\n# **Vision**\n\nIn an era where technology is reshaping healthcare, our team proposes an innovative approach to revolutionize clinical trials. Our vision is to create a new paradigm in clinical trials - one that is more inclusive, equitable, and efficient. By decentralizing the research process and employing innovative technologies, we strive to open up new avenues for scientific discovery and healthcare advancements, making clinical research accessible to all.\n\n# **Issue Statement**\n\nOur project is designed to address several pivotal challenges in the field of clinical trials. We are targeting the substantial difficulty in accessing and effectively utilizing real-world health data, which is often constrained within isolated data silos. This situation impedes its potential use in health innovation and research, further complicated by organizational, legal, and technical barriers. Additionally, we are tackling issues such as low participant engagement and compliance in clinical trials, leading to incomplete or biased data. Furthermore, we are focusing on overcoming the limited accessibility of traditional trials, which often present geographical and logistical barriers that restrict diverse population participation. Finally, our project aims to address data privacy concerns, a significant hurdle in convincing participants to share personal health data. By introducing a decentralized model for clinical trials and enabling direct data sharing from individuals, we intend to enhance the efficiency of data collection, improve participant engagement, and foster more inclusive and diverse research.\n\n# **Solution** \n\nOur proposed solution integrates advanced technology and a decentralized approach to address key challenges in clinical trials. It encompasses:\n\n- **Advanced Technology Integration:** Utilizing MCS Data Labs' proprietary smartwatches equipped with sensors for comprehensive bio and environmental data collection. This technology, supported by custom software and AI/XAI algorithms, ensures efficient data capture and processing.\n- **Decentralized Clinical Trials Infrastructure:** Shifting from traditional models, we aim to create an open-source platform that democratizes the research process, allowing diverse groups to conduct their own clinical trials.\n- **Emphasis on Privacy and Data Sovereignty:** By incorporating Web3 technologies like sharding and ZK proofs, we ensure enhanced privacy and data security, giving users complete control over their data.\n- **Tokenomics for Participant Compliance:** Introducing a tokenomics model, we incentivize participants through smart contracts, promoting adherence to trial protocols.\n- **Community-Driven Research Ecosystem:** Implementing a DAO structure, our project allows community members, including patients and researchers, to actively participate in the research process, fostering a democratic, privacy-preserving approach.\n\n# **Background & Upcoming Plans**\n\nOur team's background in developing a privacy-preserving, unbiased clinical trial platform began with a pivotal moment at the ZuHack event in Istanbul last November. During this event, we focused on enhancing the privacy aspects of our technology while conducting a small-scale pilot with proprietary smart devices. Our efforts and innovative approach were recognized, as we won two awards in the DeSci and ZK categories. This success validated our initial hypotheses and set the foundation for our ongoing work. Building on this momentum, we are now preparing for a more extensive pilot at the next Zuzalu, aiming to further advance our platform and its capabilities. For more details on our submission at ZuHack, please visit the [DoraHacks project page](https://dorahacks.io/buidl/7963).\n\n**We plan to conduct decentralized clinical trials during Zuzalu 2024.** Aiming to equip residents with our wearables, while remotely collecting and monitoring data in a privacy-preserving fashion over 2 months.\n\nTo prepare for this, we will run a pilot in collaboration with Lemonade DAO and their network state protocol in Zanzibar to further test the infrastructure in May/June 2024.\n\n___\n\n# **Collaboration Synergy**\n\n**MCS Data Labs:** Bringing a wealth of expertise in hardware research and development, MCS Data Labs contributes its comprehensive skills in custom hardware, software, and AI/XAI algorithm development. This expertise is crucial for the accurate and efficient collection and processing of bio and environmental data through state-of-the-art wearable technology.\n\n**Transience Labs:** With its innovative vision of \u201cmintable moments\u201d, Transience Labs adds a unique perspective to the project. Their focus on open-source protocol architecture ensures that the infrastructure developed is not only robust and scalable but also accessible to a wide range of users and researchers.\n\n# **Why dTrials need blockchain technology?**\n\nOur platform's reliance on blockchain is not just a feature; it's a fundamental necessity to ensure the highest standards of data integrity, privacy, and security throughout its lifecycle. The integration of various cryptographic methods is pivotal in fortifying our ecosystem's security and maintaining its tamper-proof nature. These methods are intricately woven into different components of our platform, each serving a critical role. An in-depth description can be found [here](https://dtrials.gitbook.io/dtrials/project-overview/why-use-blockchain).", "lastUpdated": 0, "projectGithub": "dTrials"}, "recipient": "0xe4b6cd734a204F435807501Aa0fE5bD3865F210E"}}