{"signature": "0xc0078ae0a3b07da311527d37edb8199d2c203c6a41ca7d1b419bf368b54115502bcb47cde4e08a6043e2bc143367aac71ee77affc858c54d6c144ad16f5de1be1c", "application": {"round": "0x7b150594d8d758bcb2c3f855ffab3ece27ad2983", "answers": [{"type": "email", "hidden": true, "question": "Email Address", "questionId": 0, "encryptedAnswer": {"ciphertext": "bnygiQPbZJjM2VFGWfqZ+p0HCmrDP9NJBXcxbWmmjCBU1NYITvyIjYKrJYkEsS8k", "encryptedSymmetricKey": "530b48ebaccf6aa613ba656b239ca728c3c9de604d419f4b27cee38c7b781cd76804f49ccc3cf349e3b727273654161167b41c1891b04f7aede956db566d3016e93ce267d8cfd10589e7ed9d0ee9064f6edcfa3169f1f0b402dde0de7d46ae857aa24cf80e4c50a5b5a25eade2cbcb8358ff38ca2d7374793a2043efd6f147ca0000000000000020d0e8328e72317b8ff4ece133d734d44eea2e084d3fcc42cd33853f95c17d7fed8a6c650c7168bf55f6d5a4c1978b10a9"}}, {"type": "short-answer", "answer": "Grants", "hidden": false, "question": "Funding Sources", "questionId": 1}, {"type": "number", "answer": "2", "hidden": false, "question": "Team Size", "questionId": 2}, {"type": "short-answer", "answer": "marco_poscidondao", "hidden": true, "question": "Telegram username", "questionId": 3}, {"type": "paragraph", "answer": "371.45 USD", "hidden": true, "question": "Total prior funding for project in USD", "questionId": 4}, {"type": "paragraph", "answer": "Ayat Abourashed - https://twitter.com/ayatabourashed ", "hidden": true, "question": "Profiles or socials of other main team members publicly associated with project", "questionId": 5}, {"type": "paragraph", "answer": "8", "hidden": true, "question": "How old is the project? (Months)", "questionId": 6}, {"type": "paragraph", "answer": "Problem\nThe current \"one-size-fits-all\" healthcare approach causes high treatment failure rates, necessitating a shift to personalized medicine (PM) for better patient outcomes. However, PM research requires significant amounts of funding, but, unfortunately, scientific funding comes with its own set of systemic problems. \n\nThe scientific research funding landscape is overrun by centralization and bias, with issues rooted in economic, political and institutional influences often diverting funds from merit-based projects. These challenges include inequities in regional and demographic funding, a tendency to prioritize certain fields and short-term gains and a concentration of resources that disadvantages less established researchers, including early-career researchers. In some cases, funding can even be revoked based on arbitrary reasons not based on the science or its output. Biases in evaluation and peer review processes further exacerbate these disparities, stifling diversity and innovation. PoSciDonDAO aims to dismantle these barriers through a decentralized application and token system that incentivizes collaboration, transparency and daring research, thus optimizing scientific efficiency and maximizing scientific impact.\n\nSolution\nTo overcome these issues in scientific research funding, we created PoSciDonDAO. PoSciDonDAO is a decentralized autonomous organization (DAO) that leverages Polygon's blockchain to redefine the funding of PM research. By doing so, PoSciDonDAO accelerates breakthroughs in PM, setting the stage for a future where healthcare is predictive, personalized and patient-centric. Its dual-token and dual-on-chain governance models facilitate efficient, transparent and unbiased resource allocation to fund research projects advancing treatments for life-altering diseases including cancer and multiple sclerosis.\n\nImplementation\n1. Conceptualization of on-chain infrastructure including token economics, donations platform, staking and governance (completed, see whitepaper: https://www.poscidondao.com/Whitepaper.pdf).\n2. Development of on-chain infrastructure (work in progress).\n     - On-chain donations launched on mainnet (https://protocol.poscidondao.com/donate)\n     - Staking & governance smart contracts on testnet (awaiting audit)\n3. Attract research proposals and expert contributors (ongoing)\n4. Establishing a community of scientists, investors, bio-entrepreneurs and DeSci-enthusiasts (ongoing)\n5. Commercialize PM research output to establish a sustainable DAO\n\nShort-term roadmap:\n\nApril 8-30\n- Publish \u201cIntroduction to PoSciDonDAO\u201d Medium articles\n- Organize first Twitter Space\n- Publish Gitbook litepaper\n- Audit $SCI token smart contract\n\nMay 1-14\n- Medium Article about $SCI launch\n- Progress update Twitter Space\n- KYC on Pinksale\n- Deploy $SCI smart contract\n- Project verification on Fjord Foundry (FF)\n\nMay 15-31\n- $SCI pre-sale on dApp\n- $SCI Pinksale\n- Token launch Twitter Space\n- Finalize frontend for governance systems\n\nJune 1-14\n- Finance Curator on Fjord Foundry\n- Launch $SCI on Fjord Foundry\n- AMA Twitter Space\n\nJune 15-30\n- Create liquidity pools for $SCI on Uniswap\n- DeSci topic Twitter Space\n\nJuly 1-14\n- Audit governance and staking smart contracts\n- dApp overview Twitter Space\n\nJuly 15-31\n- Open funding proposal applications\n- Deploy dApp when audits are complete\n\nRest of Q3\n- Reviewing research proposals and selecting first projects for funding", "hidden": false, "question": "Describe your project in a few paragraphs (ideally including a problem statement, solution, roadmap, and timeline for implementation)", "questionId": 7}, {"type": "paragraph", "answer": "PoSciDonDAO will be governed by the PoSciDonDAO protocol, a set of smart contracts including staking and governance smart contracts for DAO Operations and Research Funding. This makes PoSciDonDAO the first on-chain DeSci DAO, ensuring that funding of personalized medicine research is decentralized. \n\nUsing this on-chain system, we can overcome several issues in science and DeSci. \n\nIn current DeSci DAOs, DAO members that are not scientific experts are required to evaluate scientific research projects. To ensure that mainly expert scientific DAO members will source and review scientific research projects, we created a governance system consisting of two smart contracts: Research Funding and DAO Operations. \n\nResearch Funding governance will include on-chain execution of passed proposals in USDC, MATIC and PoSciDonDAO\u2019s token, called SCI (launch in 2024), ensuring transparency in the distribution of funds towards scientific research projects. In addition, this makes the on-chain proposals binding, meaning that PoSciDonDAO cannot back out of the passed proposal. The Research Funding governance system will be governed by elected scientific DAO members, ensuring that research projects are evaluated by experts in their field, while relieving non-scientific members from decision-making in specialized areas beyond their expertise. These expert scientific members governing Research Funding will be elected through the DAO Operations governance where anyone can participate as long as the member has staked SCI through the dApp. \n\nBesides the election of the expert scientific members, other aspects of the organization\u2019s operations can also be governed through the DAO Operations governance smart contract. This governance system consists of several features including delegation of votes and quadratic voting. The distribution of funds in the form of USDC, MATIC and SCI will also be performed on-chain. Altogether, these features make the DAO Operations governance smart contract a robust system.\n\nQuadratic voting can, to some degree, be bypassed by sending tokens to other wallets to further increase the user's total voting power. To overcome that, we implemented Holonym in the dApp. This implementation checks if users have minted a soul-bound token to their account through Holonym's platform after verification of their phone number or government identification. This ensures that only unique accounts/one individual can vote on proposals with quadratic voting enabled. \n\nAnother common issue among DAOs is the lack of participation by members in its governance system. To incentivize members to participate in our Operations governance, members receive a non-tradable, non-fungible token called PO that can be exchanged for rewards including SCI tokens and, in the future, merch, conference tickets and other products. \n", "hidden": false, "question": "How does your project support the mission or goals of DeSci?", "questionId": 8}, {"type": "paragraph", "answer": "Funds will primarily be used for dApp development and community building. Our goal is to have several smart contracts audited before the token launch so we will designate a significant portion of funds to do this. A substantial portion would also be used to accelerate the refinement of our current dApp. This includes further enhancing the user interface and user experience for better accessibility and onboarding of users not familiar with web3.\n \nRegarding community building, funds will be used to expand our outreach and to foster engagement through marketing campaigns, social media content, DeSci hackathons and collaborative events including conferences and workshops. Through these events we aim to inform existing and new members about the need for decentralized science and about PoSciDonDAO's impact on science and healthcare innovation. Many of the organized events will be done in collaboration with research institutes and cutting-edge biotech companies.", "hidden": false, "question": "Describe how funds from the grants program will be used for your project.", "questionId": 9}, {"type": "paragraph", "hidden": true, "question": "If you participated in past grant rounds (i.e. DeSci GR15/ Beta) using a different project payout wallet address, please share it here.", "questionId": 10}, {"type": "paragraph", "answer": "Since our participation in the HyperDeSci round organized by LunCo, we have launched our on-chain donations platform on Polygon mainnet. Through this platform, donated funds will go to personalized medicine research projects selected by PoSciDonDAO. We have been highlighted by AxonDAO through their twitter spaces and we already received project proposals from personalized medicine researchers that are standby for funding from PoSciDonDAO.", "hidden": false, "question": "If this project participated in past DeSci grant rounds, please share any new updates or milestones since the last round.", "questionId": 11}, {"type": "paragraph", "hidden": true, "question": "Is there any other information you would like to share about your project, previous work, other project affiliations, or potential conflicts of interest? (or anything not covered elsewhere in this application that you feel is relevant to share)", "questionId": 12}, {"type": "dropdown", "answer": "Yes", "hidden": false, "question": "Does 50% of your team reflect the diversity of the community your project serves with a particular emphasis on including women, Black, Indigenous, and People of Color (BIPoC), individuals with disabilities, and members of the LGBTQ+ community?", "questionId": 13}, {"type": "multiple-choice", "hidden": true, "question": "Please read the following exclusion criteria that are not permitted and will result in rejection or removal from the round.", "questionId": 14}], "project": {"id": "0x7ea8c4ebe8d6307efe7492f8b41da2e4e487a2cef99f2174cf42b570d3dac7d0", "title": "PoSciDonDAO", "logoImg": "bafkreiaz63fpaj3odea473mpqlp3ffteominewnbjqwqleeo6x6kap4ks4", "metaPtr": {"pointer": "bafkreibvuzjz2prb6jjo6rz4srhrjptlgwuc34dz63kjtjqcelwc457fia", "protocol": "undefined"}, "website": "https://www.poscidondao.com", "bannerImg": "bafkreigbheekqejvb4ykwcxbs57zbn6chjeb7ezzy5v4ilk4okgewsgt2q", "createdAt": 1710352847384, "userGithub": "Marrmee", "credentials": {"github": {"type": ["VerifiableCredential"], "proof": {"jws": "eyJhbGciOiJFZERTQSIsImNyaXQiOlsiYjY0Il0sImI2NCI6ZmFsc2V9..Vb5iwhqlSUoaU1QCXe2OP1_iRTIuyL8ZO8P9O8d-2Mo-wBPtEVGsukbquN6799H_NUD-OC22YDjNJeXbOWotDw", "type": "Ed25519Signature2018", "created": "2024-04-03T18:48:02.784Z", "proofPurpose": "assertionMethod", "verificationMethod": "did:key:z6MkghvGHLobLEdj1bgRLhS4LPGJAvbMA1tn2zcRyqmYU5LC#z6MkghvGHLobLEdj1bgRLhS4LPGJAvbMA1tn2zcRyqmYU5LC"}, "issuer": "did:key:z6MkghvGHLobLEdj1bgRLhS4LPGJAvbMA1tn2zcRyqmYU5LC", "@context": ["https://www.w3.org/2018/credentials/v1"], "issuanceDate": "2024-04-03T18:48:02.784Z", "expirationDate": "2024-07-02T18:48:02.784Z", "credentialSubject": {"id": "did:pkh:eip155:1:0x690BF2dB31D39EE0a88fcaC89117b66a588E865a", "hash": "v0.0.0:gCJ9m4W9HjdbDEPltUq97xdeu47dRP4ViKUqhlIe5nQ=", "@context": [{"hash": "https://schema.org/Text", "provider": "https://schema.org/Text"}], "provider": "ClearTextGithubOrg#PoSciDonDAO#96262582"}}, "twitter": {"type": ["VerifiableCredential"], "proof": {"jws": "eyJhbGciOiJFZERTQSIsImNyaXQiOlsiYjY0Il0sImI2NCI6ZmFsc2V9..C31B-XjwDzLh71yNrlHmueIGuqTYKzYZRaxgsjedCmTpXH2pDjdClOGOiI5E66ot-GkrmAjDKdH65jMNalegDw", "type": "Ed25519Signature2018", "created": "2024-03-13T17:53:22.574Z", "proofPurpose": "assertionMethod", "verificationMethod": "did:key:z6MkghvGHLobLEdj1bgRLhS4LPGJAvbMA1tn2zcRyqmYU5LC#z6MkghvGHLobLEdj1bgRLhS4LPGJAvbMA1tn2zcRyqmYU5LC"}, "issuer": "did:key:z6MkghvGHLobLEdj1bgRLhS4LPGJAvbMA1tn2zcRyqmYU5LC", "@context": ["https://www.w3.org/2018/credentials/v1"], "issuanceDate": "2024-03-13T17:53:22.573Z", "expirationDate": "2024-06-11T17:53:22.573Z", "credentialSubject": {"id": "did:pkh:eip155:1:0x690BF2dB31D39EE0a88fcaC89117b66a588E865a", "hash": "v0.0.0:5KvqubmJH+I66cKOwG/x/jBbatwfk9329+7BSc0jnBA=", "@context": [{"hash": "https://schema.org/Text", "provider": "https://schema.org/Text"}], "provider": "ClearTextTwitter#PoSciDonDAO"}}}, "description": "The current \"one-size-fits-all\" healthcare approach causes high treatment failure rates, necessitating a shift to personalized medicine (PM) for better patient outcomes. However, PM research requires significant amounts of funding, but, unfortunately, scientific funding comes with its own set of systemic problems. PoSciDonDAO is a decentralized autonomous organization that leverages Polygon's blockchain to redefine PM research funding. By doing so, PoSciDonDAO accelerates breakthroughs in PM, setting the stage for a future where healthcare is predictive, personalized and patient-centric. Its dual-token and dual-on-chain governance models facilitate efficient, transparent and unbiased resource allocation to fund research projects advancing treatments for life-altering diseases including cancer and multiple sclerosis. ", "lastUpdated": 0, "projectGithub": "PoSciDonDAO", "projectTwitter": "PoSciDonDAO"}, "recipient": "0x681237e285d8630e992D2DbbDd8F2FAf1435bD36"}}